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Research Article

Learning a Prior on Regulatory Potential from eQTL Data

  • Su-In Lee,

    Affiliation: Computer Science Department, Stanford University, Stanford, California, United States of America

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  • Aimée M. Dudley,

    Affiliation: Institute for Systems Biology, Seattle, Washington, United States of America

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  • David Drubin,

    Affiliation: Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Pamela A. Silver,

    Affiliation: Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Nevan J. Krogan,

    Affiliation: Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, California, United States of America

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  • Dana Pe'er,

    Affiliation: Department of Biological Sciences, Columbia University, New York, New York, United States of America

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  • Daphne Koller mail

    koller@cs.stanford.edu

    Affiliation: Computer Science Department, Stanford University, Stanford, California, United States of America

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  • Published: January 30, 2009
  • DOI: 10.1371/journal.pgen.1000358

About the Authors

Su-In Lee, Daphne Koller
Computer Science Department, Stanford University, Stanford, California, United States of America
Aimée M. Dudley
Institute for Systems Biology, Seattle, Washington, United States of America
David Drubin, Pamela A. Silver
Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America
Nevan J. Krogan
Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, California, United States of America
Dana Pe'er
Department of Biological Sciences, Columbia University, New York, New York, United States of America

Corresponding Author

Email: koller@cs.stanford.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SIL AMD DK. Performed the experiments: SIL AMD. Analyzed the data: SIL AMD DP DK. Contributed reagents/materials/analysis tools: SIL. Wrote the paper: SIL DK. Assisted in the performance of the microscopy experiments: DD PAS. Generated and analyzed the EMAP data: NJK.