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Research Article

A Genome-Wide Association Study Identifies Novel and Functionally Related Susceptibility Loci for Kawasaki Disease

  • David Burgner equal contributor mail,

    equal contributor Contributed equally to this work with: David Burgner, Sonia Davila

    dburgner@meddent.uwa.edu.au

    Affiliation: School of Pediatrics and Child Health, University of Western Australia, Perth, Australia

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  • Sonia Davila equal contributor,

    equal contributor Contributed equally to this work with: David Burgner, Sonia Davila

    Affiliation: Infectious Diseases, Genome Institute of Singapore, Singapore, Singapore

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  • Willemijn B. Breunis,

    Affiliation: Division of Pediatric Hematology, Immunology, and Infectious Diseases, Emma Children's Hospital Academic Medical Center, Amsterdam, The Netherlands

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  • Sarah B. Ng,

    Affiliation: Infectious Diseases, Genome Institute of Singapore, Singapore, Singapore

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  • Yi Li,

    Affiliation: Human Genetics Programme, Genome Institute of Singapore, Singapore, Singapore

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  • Carine Bonnard,

    Affiliation: Human Genetics Programme, Genome Institute of Singapore, Singapore, Singapore

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  • Ling Ling,

    Affiliation: Infectious Diseases, Genome Institute of Singapore, Singapore, Singapore

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  • Victoria J. Wright,

    Affiliation: Department of Pediatrics, Division of Medicine, Imperial College London, London, United Kingdom

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  • Anbupalam Thalamuthu,

    Affiliation: Human Genetics Programme, Genome Institute of Singapore, Singapore, Singapore

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  • Miranda Odam,

    Affiliation: School of Pediatrics and Child Health, University of Western Australia, Perth, Australia

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  • Chisato Shimizu,

    Affiliation: Department of Pediatrics, University of California San Diego School of Medicine, Rady Children's Hospital, San Diego, California, United States of America

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  • Jane C. Burns,

    Affiliation: Department of Pediatrics, University of California San Diego School of Medicine, Rady Children's Hospital, San Diego, California, United States of America

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  • Michael Levin,

    Affiliation: Department of Pediatrics, Division of Medicine, Imperial College London, London, United Kingdom

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  • Taco W. Kuijpers,

    Affiliation: Division of Pediatric Hematology, Immunology, and Infectious Diseases, Emma Children's Hospital Academic Medical Center, Amsterdam, The Netherlands

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  • Martin L. Hibberd,

    Affiliation: Infectious Diseases, Genome Institute of Singapore, Singapore, Singapore

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  • International Kawasaki Disease Genetics Consortium
  • Published: January 09, 2009
  • DOI: 10.1371/journal.pgen.1000319

About the Authors

David Burgner, Miranda Odam
School of Pediatrics and Child Health, University of Western Australia, Perth, Australia
Sonia Davila, Sarah B. Ng, Ling Ling, Martin L. Hibberd
Infectious Diseases, Genome Institute of Singapore, Singapore, Singapore
Willemijn B. Breunis, Taco W. Kuijpers
Division of Pediatric Hematology, Immunology, and Infectious Diseases, Emma Children's Hospital Academic Medical Center, Amsterdam, The Netherlands
Yi Li, Carine Bonnard, Anbupalam Thalamuthu
Human Genetics Programme, Genome Institute of Singapore, Singapore, Singapore
Victoria J. Wright, Michael Levin
Department of Pediatrics, Division of Medicine, Imperial College London, London, United Kingdom
Chisato Shimizu, Jane C. Burns
Department of Pediatrics, University of California San Diego School of Medicine, Rady Children's Hospital, San Diego, California, United States of America

Corresponding Author

Email: dburgner@meddent.uwa.edu.au

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DB SD WBB TWK MLH. Performed the experiments: SBN CB LL. Analyzed the data: DB SD SBN YL CB LL AT MLH. Contributed reagents/materials/analysis tools: DB SD WBB YL VJW MO CS JCB ML TWK MLH. Wrote the paper: DB SD MLH.