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Research Article

Genetic Control of Variegated KIR Gene Expression: Polymorphisms of the Bi-Directional KIR3DL1 Promoter Are Associated with Distinct Frequencies of Gene Expression

  • Hongchuan Li,

    Affiliations: Basic Research Program, SAIC-Frederick Inc., National Cancer Institute-Frederick, Frederick, Maryland, United States of America, Cancer and Inflammation Program, Laboratory of Experimental Immunology, Center for Cancer Research, National Cancer Institute-Frederick, Frederick, Maryland, United States of America

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  • Véronique Pascal,

    Affiliation: Cancer and Inflammation Program, Laboratory of Experimental Immunology, Center for Cancer Research, National Cancer Institute-Frederick, Frederick, Maryland, United States of America

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  • Maureen P. Martin,

    Affiliations: Basic Research Program, SAIC-Frederick Inc., National Cancer Institute-Frederick, Frederick, Maryland, United States of America, Cancer and Inflammation Program, Laboratory of Experimental Immunology, Center for Cancer Research, National Cancer Institute-Frederick, Frederick, Maryland, United States of America

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  • Mary Carrington,

    Affiliations: Basic Research Program, SAIC-Frederick Inc., National Cancer Institute-Frederick, Frederick, Maryland, United States of America, Cancer and Inflammation Program, Laboratory of Experimental Immunology, Center for Cancer Research, National Cancer Institute-Frederick, Frederick, Maryland, United States of America

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  • Stephen K. Anderson mail

    andersonst@mail.nih.gov

    Affiliations: Basic Research Program, SAIC-Frederick Inc., National Cancer Institute-Frederick, Frederick, Maryland, United States of America, Cancer and Inflammation Program, Laboratory of Experimental Immunology, Center for Cancer Research, National Cancer Institute-Frederick, Frederick, Maryland, United States of America

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  • Published: November 14, 2008
  • DOI: 10.1371/journal.pgen.1000254

About the Authors

Hongchuan Li, Maureen P. Martin, Mary Carrington, Stephen K. Anderson
Basic Research Program, SAIC-Frederick Inc., National Cancer Institute-Frederick, Frederick, Maryland, United States of America
Hongchuan Li, Véronique Pascal, Maureen P. Martin, Mary Carrington, Stephen K. Anderson
Cancer and Inflammation Program, Laboratory of Experimental Immunology, Center for Cancer Research, National Cancer Institute-Frederick, Frederick, Maryland, United States of America

Corresponding Author

Email: andersonst@mail.nih.gov

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MC SKA. Performed the experiments: HL VP MPM. Analyzed the data: HL VP MPM MC SKA. Wrote the paper: MC SKA.