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Research Article

p8/TTDA Overexpression Enhances UV-Irradiation Resistance and Suppresses TFIIH Mutations in a Drosophila Trichothiodystrophy Model

  • Javier Aguilar-Fuentes,

    Affiliation: Department of Developmental Genetics, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, México

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  • Mariana Fregoso,

    Affiliation: Department of Developmental Genetics, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, México

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  • Mariana Herrera,

    Affiliation: Department of Developmental Genetics, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, México

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  • Enrique Reynaud,

    Affiliation: Department of Developmental Genetics, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, México

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  • Cathy Braun,

    Affiliation: Institut de Génétique et de Biologie Moléculaire et Cellulaire, C.U. de Strasbourg, France

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  • Jean Marc Egly,

    Affiliation: Institut de Génétique et de Biologie Moléculaire et Cellulaire, C.U. de Strasbourg, France

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  • Mario Zurita mail

    marioz@ibt.unam.mx

    Affiliation: Department of Developmental Genetics, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, México

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  • Published: November 14, 2008
  • DOI: 10.1371/journal.pgen.1000253

About the Authors

Javier Aguilar-Fuentes, Mariana Fregoso, Mariana Herrera, Enrique Reynaud, Mario Zurita
Department of Developmental Genetics, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, México
Cathy Braun, Jean Marc Egly
Institut de Génétique et de Biologie Moléculaire et Cellulaire, C.U. de Strasbourg, France

Corresponding Author

Email: marioz@ibt.unam.mx

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MF ER JME MZ. Performed the experiments: JAF MF MH ER CB. Analyzed the data: JAF MF JME MZ. Wrote the paper: MZ.