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Research Article

Adaptive Copy Number Evolution in Malaria Parasites

  • Shalini Nair,

    Affiliation: Southwest Foundation for Biomedical Research (SFBR), San Antonio, Texas, United States of America

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  • Becky Miller,

    Affiliation: Department of Biological Sciences, Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, United States of America

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  • Marion Barends,

    Affiliations: Shoklo Malaria Research Unit (SMRU), Mae Sot, Tak, Thailand, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

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  • Anchalee Jaidee,

    Affiliation: Shoklo Malaria Research Unit (SMRU), Mae Sot, Tak, Thailand

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  • Jigar Patel,

    Affiliation: Roche NimbleGen, Inc., Madison, Wisconsin, United States of America

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  • Mayfong Mayxay,

    Affiliations: Wellcome Trust–Mahosot Hospital–Oxford Tropical Medicine Research Collaboration, Mahosot Hospital, Vientiane, Lao People's Democratic Republic, Department of Post Graduates and Research, Faculty of Medical Science, National University of Laos, Vientiane, Lao People's Democratic Republic

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  • Paul Newton,

    Affiliations: Wellcome Trust–Mahosot Hospital–Oxford Tropical Medicine Research Collaboration, Mahosot Hospital, Vientiane, Lao People's Democratic Republic, Centre for Tropical Medicine and Vaccinology, Churchill Hospital, Oxford, United Kingdom

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  • François Nosten,

    Affiliations: Shoklo Malaria Research Unit (SMRU), Mae Sot, Tak, Thailand, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, Centre for Tropical Medicine and Vaccinology, Churchill Hospital, Oxford, United Kingdom

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  • Michael T. Ferdig,

    Affiliation: Department of Biological Sciences, Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, United States of America

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  • Tim J. C. Anderson mail

    tanderso@sfbrgenetics.org

    Affiliation: Southwest Foundation for Biomedical Research (SFBR), San Antonio, Texas, United States of America

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  • Published: October 31, 2008
  • DOI: 10.1371/journal.pgen.1000243

About the Authors

Shalini Nair, Tim J. C. Anderson
Southwest Foundation for Biomedical Research (SFBR), San Antonio, Texas, United States of America
Becky Miller, Michael T. Ferdig
Department of Biological Sciences, Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, United States of America
Marion Barends, Anchalee Jaidee, François Nosten
Shoklo Malaria Research Unit (SMRU), Mae Sot, Tak, Thailand
Marion Barends, François Nosten
Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
Jigar Patel
Roche NimbleGen, Inc., Madison, Wisconsin, United States of America
Mayfong Mayxay, Paul Newton
Wellcome Trust–Mahosot Hospital–Oxford Tropical Medicine Research Collaboration, Mahosot Hospital, Vientiane, Lao People's Democratic Republic
Mayfong Mayxay
Department of Post Graduates and Research, Faculty of Medical Science, National University of Laos, Vientiane, Lao People's Democratic Republic
Paul Newton, François Nosten
Centre for Tropical Medicine and Vaccinology, Churchill Hospital, Oxford, United Kingdom

Corresponding Author

Email: tanderso@sfbrgenetics.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SN JP MTF TJCA. Performed the experiments: SN BM JP. Analyzed the data: SN MTF TJCA. Contributed reagents/materials/analysis tools: BM MB AJ MM PN FN. Wrote the paper: SN MTF TJCA.