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Research Article

Diverse Splicing Patterns of Exonized Alu Elements in Human Tissues

  • Lan Lin,

    Affiliation: Department of Internal Medicine, University of Iowa, Iowa City, Iowa, United States of America

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  • Shihao Shen,

    Affiliation: Department of Biostatistics, University of Iowa, Iowa City, Iowa, United States of America

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  • Anne Tye,

    Affiliation: Department of Internal Medicine, University of Iowa, Iowa City, Iowa, United States of America

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  • James J. Cai,

    Affiliation: Department of Biology, Stanford University, Stanford, California, United States of America

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  • Peng Jiang,

    Affiliation: Department of Internal Medicine, University of Iowa, Iowa City, Iowa, United States of America

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  • Beverly L. Davidson,

    Affiliations: Department of Internal Medicine, University of Iowa, Iowa City, Iowa, United States of America, Department of Molecular Physiology and Biophysics, University of Iowa, Iowa City, Iowa, United States of America, Department of Neurology, University of Iowa, Iowa City, Iowa, United States of America

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  • Yi Xing mail

    yi-xing@uiowa.edu

    Affiliations: Department of Internal Medicine, University of Iowa, Iowa City, Iowa, United States of America, Department of Biomedical Engineering, University of Iowa, Iowa City, Iowa, United States of America

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  • Published: October 17, 2008
  • DOI: 10.1371/journal.pgen.1000225

About the Authors

Lan Lin, Anne Tye, Peng Jiang, Beverly L. Davidson, Yi Xing
Department of Internal Medicine, University of Iowa, Iowa City, Iowa, United States of America
Shihao Shen
Department of Biostatistics, University of Iowa, Iowa City, Iowa, United States of America
James J. Cai
Department of Biology, Stanford University, Stanford, California, United States of America
Beverly L. Davidson
Department of Molecular Physiology and Biophysics, University of Iowa, Iowa City, Iowa, United States of America
Beverly L. Davidson
Department of Neurology, University of Iowa, Iowa City, Iowa, United States of America
Yi Xing
Department of Biomedical Engineering, University of Iowa, Iowa City, Iowa, United States of America

Corresponding Author

Email: yi-xing@uiowa.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LL YX. Performed the experiments: LL SS AT JJC PJ YX. Analyzed the data: LL SS JJC YX. Contributed reagents/materials/analysis tools: SS JJC BLD YX. Wrote the paper: LL YX.