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Research Article

The Genome of Borrelia recurrentis, the Agent of Deadly Louse-Borne Relapsing Fever, Is a Degraded Subset of Tick-Borne Borrelia duttonii

  • Magali Lescot,

    Affiliation: Structural and Genomic Information Laboratory, CNRS UPR2589, IFR88, Parc Scientifique de Luminy, Marseille, France

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  • Stéphane Audic,

    Affiliation: Structural and Genomic Information Laboratory, CNRS UPR2589, IFR88, Parc Scientifique de Luminy, Marseille, France

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  • Catherine Robert,

    Affiliation: Unité des Rickettsies, UMR CNRS-IRD 6236, IFR48, Faculté de Médecine, Université de la Méditerranée, Marseille, France

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  • Thi Tien Nguyen,

    Affiliation: Unité des Rickettsies, UMR CNRS-IRD 6236, IFR48, Faculté de Médecine, Université de la Méditerranée, Marseille, France

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  • Guillaume Blanc,

    Affiliation: Structural and Genomic Information Laboratory, CNRS UPR2589, IFR88, Parc Scientifique de Luminy, Marseille, France

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  • Sally J. Cutler,

    Affiliation: School of Health and Bioscience, University of East London, Stratford, London, United Kingdom

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  • Patrick Wincker,

    Affiliation: Genoscope (CEA), Evry, France

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  • Arnaud Couloux,

    Affiliation: Genoscope (CEA), Evry, France

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  • Jean-Michel Claverie,

    Affiliation: Structural and Genomic Information Laboratory, CNRS UPR2589, IFR88, Parc Scientifique de Luminy, Marseille, France

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  • Didier Raoult,

    Affiliation: Unité des Rickettsies, UMR CNRS-IRD 6236, IFR48, Faculté de Médecine, Université de la Méditerranée, Marseille, France

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  • Michel Drancourt mail

    michel.drancourt@univmed.fr

    Affiliation: Unité des Rickettsies, UMR CNRS-IRD 6236, IFR48, Faculté de Médecine, Université de la Méditerranée, Marseille, France

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  • Published: September 12, 2008
  • DOI: 10.1371/journal.pgen.1000185

About the Authors

Magali Lescot, Stéphane Audic, Guillaume Blanc, Jean-Michel Claverie
Structural and Genomic Information Laboratory, CNRS UPR2589, IFR88, Parc Scientifique de Luminy, Marseille, France
Catherine Robert, Thi Tien Nguyen, Didier Raoult, Michel Drancourt
Unité des Rickettsies, UMR CNRS-IRD 6236, IFR48, Faculté de Médecine, Université de la Méditerranée, Marseille, France
Sally J. Cutler
School of Health and Bioscience, University of East London, Stratford, London, United Kingdom
Patrick Wincker, Arnaud Couloux
Genoscope (CEA), Evry, France

Corresponding Author

Email: michel.drancourt@univmed.fr

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DR. Performed the experiments: CR TTN PW AC. Analyzed the data: ML SA GB SJC JMC DR MD. Wrote the paper: ML SA GB SJC JMC DR MD. Performed the bioinformatic analyses: ML SA GB. Performed genome sequencing: PW AC.