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Research Article

Resolving Individuals Contributing Trace Amounts of DNA to Highly Complex Mixtures Using High-Density SNP Genotyping Microarrays

  • Nils Homer,

    Affiliations: Translational Genomics Research Institute (TGen), Phoenix, Arizona, United States of America, University of California Los Angeles, Los Angeles, California, United States of America

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  • Szabolcs Szelinger,

    Affiliation: Translational Genomics Research Institute (TGen), Phoenix, Arizona, United States of America

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  • Margot Redman,

    Affiliation: Translational Genomics Research Institute (TGen), Phoenix, Arizona, United States of America

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  • David Duggan,

    Affiliation: Translational Genomics Research Institute (TGen), Phoenix, Arizona, United States of America

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  • Waibhav Tembe,

    Affiliation: Translational Genomics Research Institute (TGen), Phoenix, Arizona, United States of America

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  • Jill Muehling,

    Affiliation: Translational Genomics Research Institute (TGen), Phoenix, Arizona, United States of America

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  • John V. Pearson,

    Affiliation: Translational Genomics Research Institute (TGen), Phoenix, Arizona, United States of America

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  • Dietrich A. Stephan,

    Affiliation: Translational Genomics Research Institute (TGen), Phoenix, Arizona, United States of America

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  • Stanley F. Nelson,

    Affiliation: University of California Los Angeles, Los Angeles, California, United States of America

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  • David W. Craig mail

    dcraig@tgen.org

    Affiliation: Translational Genomics Research Institute (TGen), Phoenix, Arizona, United States of America

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  • Published: August 29, 2008
  • DOI: 10.1371/journal.pgen.1000167

About the Authors

Nils Homer, Szabolcs Szelinger, Margot Redman, David Duggan, Waibhav Tembe, Jill Muehling, John V. Pearson, Dietrich A. Stephan, David W. Craig
Translational Genomics Research Institute (TGen), Phoenix, Arizona, United States of America
Nils Homer, Stanley F. Nelson
University of California Los Angeles, Los Angeles, California, United States of America

Corresponding Author

Email: dcraig@tgen.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SFN DWC. Performed the experiments: SS MR JM. Analyzed the data: NH WT DWC. Contributed reagents/materials/analysis tools: DD JVP DS SFN DWC. Wrote the paper: NH DWC.