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Research Article

Incompatibilities Involving Yeast Mismatch Repair Genes: A Role for Genetic Modifiers and Implications for Disease Penetrance and Variation in Genomic Mutation Rates

  • Ann Demogines,

    Affiliation: Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America

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  • Alex Wong,

    Affiliation: Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America

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  • Charles Aquadro,

    Affiliation: Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America

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  • Eric Alani mail

    eea3@cornell.edu

    Affiliation: Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America

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  • Published: June 20, 2008
  • DOI: 10.1371/journal.pgen.1000103

About the Authors

Ann Demogines, Alex Wong, Charles Aquadro, Eric Alani
Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America

Corresponding Author

Email: eea3@cornell.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AD AW CA EA. Performed the experiments: AD AW EA. Analyzed the data: AD AW CA EA. Wrote the paper: AD AW CA EA.