Advertisement
Research Article

Geographic Patterns of Genome Admixture in Latin American Mestizos

  • Sijia Wang,

    Affiliation: The Galton Laboratory, Department of Biology, University College London, London, United Kingdom

    X
  • Nicolas Ray,

    Affiliation: Computational and Molecular Population Genetics Laboratory, University of Bern, Bern, Switzerland

    X
  • Winston Rojas,

    Affiliation: Laboratorio de Genética Molecular, Universidad de Antioquia, Medellín, Colombia

    X
  • Maria V. Parra,

    Affiliation: Laboratorio de Genética Molecular, Universidad de Antioquia, Medellín, Colombia

    X
  • Gabriel Bedoya,

    Affiliation: Laboratorio de Genética Molecular, Universidad de Antioquia, Medellín, Colombia

    X
  • Carla Gallo,

    Affiliation: Laboratorios de Investigación y Desarrollo, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima, Perú

    X
  • Giovanni Poletti,

    Affiliation: Laboratorios de Investigación y Desarrollo, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima, Perú

    X
  • Guido Mazzotti †,

    † Deceased.

    Affiliation: Facultad de Medicina, Universidad Peruana Cayetano Heredia, Lima, Perú

    X
  • Kim Hill,

    Affiliation: Department of Anthropology, University of New Mexico, Albuquerque, New Mexico, United States of America

    X
  • Ana M. Hurtado,

    Affiliation: Department of Anthropology, University of New Mexico, Albuquerque, New Mexico, United States of America

    X
  • Beatriz Camrena,

    Affiliation: Departamento de Ciencias Genómicas, Universidad Autónoma de la Ciudad de México, México D.F., México

    X
  • Humberto Nicolini,

    Affiliation: Departamento de Ciencias Genómicas, Universidad Autónoma de la Ciudad de México, México D.F., México

    X
  • William Klitz,

    Affiliations: School of Public Health, University of California Berkeley, Berkeley, California, United States of America, Public Health Institute, Oakland, California, United States of America

    X
  • Ramiro Barrantes,

    Affiliation: Escuela de Biología, Universidad de Costa Rica, San José, Costa Rica

    X
  • Julio A. Molina,

    Affiliation: Center for Neurobehavioral Genetics, University of California Los Angeles, Los Angeles, California, United States of America

    X
  • Nelson B. Freimer,

    Affiliation: Center for Neurobehavioral Genetics, University of California Los Angeles, Los Angeles, California, United States of America

    X
  • Maria Cátira Bortolini,

    Affiliation: Departamento de Genética, Instituto de Biociências, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brasil

    X
  • Francisco M. Salzano,

    Affiliation: Departamento de Genética, Instituto de Biociências, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brasil

    X
  • Maria L. Petzl-Erler,

    Affiliation: Departamento de Genética, Universidade Federal do Paraná, Curitiba, Brazil

    X
  • Luiza T. Tsuneto,

    Affiliation: Departamento de Genética, Universidade Federal do Paraná, Curitiba, Brazil

    X
  • José E. Dipierri,

    Affiliation: Instituto de Biología de la Altura, Facultad de Humanidades y Ciencias Sociales, Universidad Nacional de Jujuy, San Salvador de Jujuy, Argentina

    X
  • Emma L. Alfaro,

    Affiliation: Instituto de Biología de la Altura, Facultad de Humanidades y Ciencias Sociales, Universidad Nacional de Jujuy, San Salvador de Jujuy, Argentina

    X
  • Graciela Bailliet,

    Affiliation: Laboratory of Human Molecular Population Genetics, IMBICE, La Plata, Argentina

    X
  • Nestor O. Bianchi,

    Affiliation: Laboratory of Human Molecular Population Genetics, IMBICE, La Plata, Argentina

    X
  • Elena Llop,

    Affiliation: Programa de Genética Humana, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile

    X
  • Francisco Rothhammer,

    Affiliations: Programa de Genética Humana, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile, Instituto de Alta Investigación, Universidad de Tarapacá, Arica, Chile

    X
  • Laurent Excoffier,

    Affiliation: Computational and Molecular Population Genetics Laboratory, University of Bern, Bern, Switzerland

    X
  • Andrés Ruiz-Linares mail

    a.ruizlin@ucl.ac.uk

    Affiliation: The Galton Laboratory, Department of Biology, University College London, London, United Kingdom

    X
  • Published: March 21, 2008
  • DOI: 10.1371/journal.pgen.1000037

About the Authors

Sijia Wang, Andrés Ruiz-Linares
The Galton Laboratory, Department of Biology, University College London, London, United Kingdom
Nicolas Ray, Laurent Excoffier
Computational and Molecular Population Genetics Laboratory, University of Bern, Bern, Switzerland
Winston Rojas, Maria V. Parra, Gabriel Bedoya
Laboratorio de Genética Molecular, Universidad de Antioquia, Medellín, Colombia
Carla Gallo, Giovanni Poletti
Laboratorios de Investigación y Desarrollo, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima, Perú
Guido Mazzotti
Facultad de Medicina, Universidad Peruana Cayetano Heredia, Lima, Perú
Kim Hill, Ana M. Hurtado
Department of Anthropology, University of New Mexico, Albuquerque, New Mexico, United States of America
Beatriz Camrena, Humberto Nicolini
Departamento de Ciencias Genómicas, Universidad Autónoma de la Ciudad de México, México D.F., México
William Klitz
School of Public Health, University of California Berkeley, Berkeley, California, United States of America
William Klitz
Public Health Institute, Oakland, California, United States of America
Ramiro Barrantes
Escuela de Biología, Universidad de Costa Rica, San José, Costa Rica
Julio A. Molina, Nelson B. Freimer
Center for Neurobehavioral Genetics, University of California Los Angeles, Los Angeles, California, United States of America
Maria Cátira Bortolini, Francisco M. Salzano
Departamento de Genética, Instituto de Biociências, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brasil
Maria L. Petzl-Erler, Luiza T. Tsuneto
Departamento de Genética, Universidade Federal do Paraná, Curitiba, Brazil
José E. Dipierri, Emma L. Alfaro
Instituto de Biología de la Altura, Facultad de Humanidades y Ciencias Sociales, Universidad Nacional de Jujuy, San Salvador de Jujuy, Argentina
Graciela Bailliet, Nestor O. Bianchi
Laboratory of Human Molecular Population Genetics, IMBICE, La Plata, Argentina
Elena Llop, Francisco Rothhammer
Programa de Genética Humana, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile
Francisco Rothhammer
Instituto de Alta Investigación, Universidad de Tarapacá, Arica, Chile

Corresponding Author

Email: a.ruizlin@ucl.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ARL. Analyzed the data: SW NR LE ARL. Contributed reagents/materials/analysis tools: WR MP GB CG GP GM KH AH BC HN WK RB JM NF MB FS MP LT JD EA GB NB EL FR ARL. Wrote the paper: ARL. Designed and produced the figures SW NR ARL. Supervised data analysis: LE ARL.