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Research Article

New Insights into Human Nondisjunction of Chromosome 21 in Oocytes

  • Tiffany Renee Oliver mail,

    toliver@genetics.emory.edu

    Affiliation: Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America

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  • Eleanor Feingold,

    Affiliations: Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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  • Kai Yu,

    Affiliation: Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, United States of America

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  • Vivian Cheung,

    Affiliation: Departments of Pediatrics and Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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  • Stuart Tinker,

    Affiliation: Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America

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  • Maneesha Yadav-Shah,

    Affiliation: Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America

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  • Nirupama Masse,

    Affiliation: Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America

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  • Stephanie L. Sherman

    Affiliation: Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America

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  • Published: March 14, 2008
  • DOI: 10.1371/journal.pgen.1000033

About the Authors

Tiffany Renee Oliver, Stuart Tinker, Maneesha Yadav-Shah, Nirupama Masse, Stephanie L. Sherman
Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America
Eleanor Feingold
Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
Eleanor Feingold
Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
Kai Yu
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, United States of America
Vivian Cheung
Departments of Pediatrics and Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Corresponding Author

Email: toliver@genetics.emory.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TO SS. Performed the experiments: TO MY NM. Analyzed the data: TO EF KY ST SS. Contributed reagents/materials/analysis tools: VC. Wrote the paper: TO EF KY SS.