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Research Article

The C. elegans Opa1 Homologue EAT-3 Is Essential for Resistance to Free Radicals

  • Takayuki Kanazawa equal contributor,

    equal contributor Contributed equally to this work with: Takayuki Kanazawa, Mauro D. Zappaterra, Ayako Hasegawa

    Affiliation: Department of Biological Chemistry, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

    Current Address: Department of Membrane Biochemistry and Biophysics, Kyoto University, Kyoto, Japan

    X
  • Mauro D. Zappaterra equal contributor,

    equal contributor Contributed equally to this work with: Takayuki Kanazawa, Mauro D. Zappaterra, Ayako Hasegawa

    Affiliation: Department of Biological Chemistry, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

    Current Address: Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Ayako Hasegawa equal contributor,

    equal contributor Contributed equally to this work with: Takayuki Kanazawa, Mauro D. Zappaterra, Ayako Hasegawa

    Affiliation: Department of Biological Chemistry, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

    X
  • Ashley P. Wright,

    Affiliation: Department of Biological Chemistry, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

    Current Address: Division of Biology, California Institute of Technology, Pasadena, California, United States of America

    X
  • Erin D. Newman-Smith,

    Affiliation: Department of Biological Chemistry, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

    Current Address: Department of MCDB, University of California Santa Barbara, Santa Barbara, California, United States of America

    X
  • Karolyn F. Buttle,

    Affiliation: Resource for the Visualization of Biological Complexity, Wadsworth Center, Albany, New York, United States of America

    X
  • Kent McDonald,

    Affiliation: Electron Microscope Laboratory, University of California Berkeley, Berkeley, California, United States of America

    X
  • Carmen A. Mannella,

    Affiliation: Resource for the Visualization of Biological Complexity, Wadsworth Center, Albany, New York, United States of America

    X
  • Alexander M. van der Bliek mail

    avan@mednet.ucla.edu

    Affiliation: Department of Biological Chemistry, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

    X
  • Published: February 29, 2008
  • DOI: 10.1371/journal.pgen.1000022

About the Authors

Takayuki Kanazawa, Mauro D. Zappaterra, Ayako Hasegawa, Ashley P. Wright, Erin D. Newman-Smith, Alexander M. van der Bliek
Department of Biological Chemistry, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America
Karolyn F. Buttle, Carmen A. Mannella
Resource for the Visualization of Biological Complexity, Wadsworth Center, Albany, New York, United States of America
Kent McDonald
Electron Microscope Laboratory, University of California Berkeley, Berkeley, California, United States of America

Corresponding Author

Email: avan@mednet.ucla.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TK MZ AH KM CM AvdB. Performed the experiments: TK MZ AH AW EN KB KM CM. Wrote the paper: AvdB.