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Research Article

Identification of Genetic and Chemical Modulators of Zebrafish Mechanosensory Hair Cell Death

  • Kelly N. Owens equal contributor,

    equal contributor Contributed equally to this work with: Kelly N. Owens, Felipe Santos

    Affiliations: Department of Biological Structure, University of Washington, Seattle, Washington, United States of America, Virginia Merrill Bloedel Hearing Research Center, University of Washington, Seattle, Washington, United States of America, Department of Otolaryngology—Head and Neck Surgery, University of Washington, Seattle, Washington, United States of America

    X
  • Felipe Santos equal contributor,

    equal contributor Contributed equally to this work with: Kelly N. Owens, Felipe Santos

    Affiliations: Virginia Merrill Bloedel Hearing Research Center, University of Washington, Seattle, Washington, United States of America, Department of Otolaryngology—Head and Neck Surgery, University of Washington, Seattle, Washington, United States of America

    X
  • Brock Roberts,

    Affiliation: Department of Biological Structure, University of Washington, Seattle, Washington, United States of America

    X
  • Tor Linbo,

    Affiliation: Department of Biological Structure, University of Washington, Seattle, Washington, United States of America

    X
  • Allison B. Coffin,

    Affiliations: Virginia Merrill Bloedel Hearing Research Center, University of Washington, Seattle, Washington, United States of America, Department of Otolaryngology—Head and Neck Surgery, University of Washington, Seattle, Washington, United States of America

    X
  • Anna J. Knisely,

    Affiliations: Virginia Merrill Bloedel Hearing Research Center, University of Washington, Seattle, Washington, United States of America, Department of Otolaryngology—Head and Neck Surgery, University of Washington, Seattle, Washington, United States of America

    X
  • Julian A. Simon,

    Affiliation: Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

    X
  • Edwin W. Rubel,

    Affiliations: Virginia Merrill Bloedel Hearing Research Center, University of Washington, Seattle, Washington, United States of America, Department of Otolaryngology—Head and Neck Surgery, University of Washington, Seattle, Washington, United States of America, Department of Physiology and Biophysics, University of Washington, Seattle, Washington, United States of America

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  • David W. Raible mail

    draible@u.washington.edu

    Affiliations: Department of Biological Structure, University of Washington, Seattle, Washington, United States of America, Virginia Merrill Bloedel Hearing Research Center, University of Washington, Seattle, Washington, United States of America

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  • Published: February 29, 2008
  • DOI: 10.1371/journal.pgen.1000020

About the Authors

Kelly N. Owens, Brock Roberts, Tor Linbo, David W. Raible
Department of Biological Structure, University of Washington, Seattle, Washington, United States of America
Kelly N. Owens, Felipe Santos, Allison B. Coffin, Anna J. Knisely, Edwin W. Rubel, David W. Raible
Virginia Merrill Bloedel Hearing Research Center, University of Washington, Seattle, Washington, United States of America
Kelly N. Owens, Felipe Santos, Allison B. Coffin, Anna J. Knisely, Edwin W. Rubel
Department of Otolaryngology—Head and Neck Surgery, University of Washington, Seattle, Washington, United States of America
Julian A. Simon
Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
Edwin W. Rubel
Department of Physiology and Biophysics, University of Washington, Seattle, Washington, United States of America

Corresponding Author

Email: draible@u.washington.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KO FS JS ER DR. Performed the experiments: KO FS BR TL AK AC. Analyzed the data: KO FS BR AC ER DR. Contributed reagents/materials/analysis tools: JS. Wrote the paper: KO FS ER DR.