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Research Article

Transcription and Chromatin Organization of a Housekeeping Gene Cluster Containing an Integrated β-Globin Locus Control Region

  • Daan Noordermeer equal contributor,

    equal contributor Contributed equally to this work with: Daan Noordermeer, Miguel R. Branco

    Affiliation: Department of Cell Biology and Genetics, Erasmus Medical Center, Rotterdam, The Netherlands

    X
  • Miguel R. Branco equal contributor,

    equal contributor Contributed equally to this work with: Daan Noordermeer, Miguel R. Branco

    Affiliation: MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College London, London, United Kingdom

    X
  • Erik Splinter,

    Affiliation: Department of Cell Biology and Genetics, Erasmus Medical Center, Rotterdam, The Netherlands

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  • Petra Klous,

    Affiliation: Department of Cell Biology and Genetics, Erasmus Medical Center, Rotterdam, The Netherlands

    X
  • Wilfred van IJcken,

    Affiliation: Erasmus Center for Biomics, Erasmus Medical Center, Rotterdam, The Netherlands

    X
  • Sigrid Swagemakers,

    Affiliation: Erasmus Center for Bioinformatics, Erasmus Medical Center, Rotterdam, The Netherlands

    X
  • Manousos Koutsourakis,

    Affiliation: Department of Cell Biology and Genetics, Erasmus Medical Center, Rotterdam, The Netherlands

    Current address: Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

    X
  • Peter van der Spek,

    Affiliation: Erasmus Center for Bioinformatics, Erasmus Medical Center, Rotterdam, The Netherlands

    X
  • Ana Pombo mail,

    ana.pombo@csc.mrc.ac.uk (AP); w.delaat@erasmusmc.nl(WdL)

    Affiliation: MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College London, London, United Kingdom

    X
  • Wouter de Laat mail

    ana.pombo@csc.mrc.ac.uk (AP); w.delaat@erasmusmc.nl(WdL)

    Affiliation: Department of Cell Biology and Genetics, Erasmus Medical Center, Rotterdam, The Netherlands

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  • Published: March 07, 2008
  • DOI: 10.1371/journal.pgen.1000016

About the Authors

Daan Noordermeer, Erik Splinter, Petra Klous, Manousos Koutsourakis, Wouter de Laat
Department of Cell Biology and Genetics, Erasmus Medical Center, Rotterdam, The Netherlands
Miguel R. Branco, Ana Pombo
MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College London, London, United Kingdom
Wilfred van IJcken
Erasmus Center for Biomics, Erasmus Medical Center, Rotterdam, The Netherlands
Sigrid Swagemakers, Peter van der Spek
Erasmus Center for Bioinformatics, Erasmus Medical Center, Rotterdam, The Netherlands

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AP WDL. Performed the experiments: DN MRB ES PK. Analyzed the data: DN MRB. Contributed reagents/materials/analysis tools: WI SS MK PS. Wrote the paper: DN MRB WDL.