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Research Article

Positive Selection and Increased Antiviral Activity Associated with the PARP-Containing Isoform of Human Zinc-Finger Antiviral Protein

  • Julie A Kerns,

    Affiliation: Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

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  • Michael Emerman,

    Affiliations: Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

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  • Harmit S Malik mail

    To whom correspondence should be addressed. E-mail: hsmalik@fhcrc.org

    Affiliation: Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

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  • Published: January 25, 2008
  • DOI: 10.1371/journal.pgen.0040021

About the Authors

Julie A Kerns, Michael Emerman, Harmit S Malik
Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
Michael Emerman
Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

Corresponding Author

Email: hsmalik@fhcrc.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

JAK, ME, and HSM conceived and designed the experiments, performed the experiments, analyzed the data, and wrote the paper. ME contributed reagents/materials/analysis tools.