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Research Article

The cdx Genes and Retinoic Acid Control the Positioning and Segmentation of the Zebrafish Pronephros

  • Rebecca A Wingert,

    Affiliation: Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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  • Rori Selleck,

    Affiliation: Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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  • Jing Yu,

    Affiliation: Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, United States of America

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  • Huai-Dong Song,

    Affiliation: Shanghai Institute of Hematology, Rui-Jin Hospital, Shanghai Second Medical University, Shanghai, China

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  • Zhu Chen,

    Affiliation: Shanghai Institute of Hematology, Rui-Jin Hospital, Shanghai Second Medical University, Shanghai, China

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  • Anhua Song,

    Affiliations: Department of Medicine, Division of Hematology/Oncology, Children's Hospital, Boston, Massachusetts, United States of America, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

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  • Yi Zhou,

    Affiliations: Department of Medicine, Division of Hematology/Oncology, Children's Hospital, Boston, Massachusetts, United States of America, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

    X
  • Bernard Thisse,

    Affiliation: Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch, France

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  • Christine Thisse,

    Affiliation: Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch, France

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  • Andrew P McMahon,

    Affiliation: Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, United States of America

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  • Alan J Davidson mail

    To whom correspondence should be addressed. E-mail: ajdavidson@partners.org

    Affiliation: Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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  • Published: October 19, 2007
  • DOI: 10.1371/journal.pgen.0030189

About the Authors

Rebecca A Wingert, Rori Selleck, Alan J Davidson
Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America
Jing Yu, Andrew P McMahon
Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, United States of America
Huai-Dong Song, Zhu Chen
Shanghai Institute of Hematology, Rui-Jin Hospital, Shanghai Second Medical University, Shanghai, China
Anhua Song, Yi Zhou
Department of Medicine, Division of Hematology/Oncology, Children's Hospital, Boston, Massachusetts, United States of America
Anhua Song, Yi Zhou
Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America
Bernard Thisse, Christine Thisse
Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch, France

Corresponding Author

Email: ajdavidson@partners.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

RAW and AJD conceived and designed the experiments. RAW, RS, JY, and AJD performed the experiments. RAW, RS, JY, BT, CT, AM, and AJD analyzed the data. HS, ZC, YZ, BT, and CT contributed reagents and materials. RAW and AJD wrote the paper.