Advertisement
Research Article

Power to Detect Risk Alleles Using Genome-Wide Tag SNP Panels

  • Michael A Eberle equal contributor,

    equal contributor Contributed equally to this work with: Michael A Eberle, Pauline C Ng

    Affiliation: Illumina, San Diego, California, United States of America

    X
  • Pauline C Ng equal contributor,

    equal contributor Contributed equally to this work with: Michael A Eberle, Pauline C Ng

    Affiliation: Illumina, San Diego, California, United States of America

    ¤a Current address: J. Craig Venter Institute, Rockville, Maryland, United States of America

    X
  • Kenneth Kuhn,

    Affiliation: Illumina, San Diego, California, United States of America

    X
  • Lixin Zhou,

    Affiliation: Illumina, San Diego, California, United States of America

    ¤b Current address: Prognosys Biosciences, La Jolla, California, United States of America

    X
  • Daniel A Peiffer,

    Affiliation: Illumina, San Diego, California, United States of America

    X
  • Luana Galver,

    Affiliation: Illumina, San Diego, California, United States of America

    X
  • Karine A Viaud-Martinez,

    Affiliation: Illumina, San Diego, California, United States of America

    X
  • Cynthia Taylor Lawley,

    Affiliation: Illumina, San Diego, California, United States of America

    X
  • Kevin L Gunderson,

    Affiliation: Illumina, San Diego, California, United States of America

    X
  • Richard Shen mail,

    To whom correspondence should be addressed. E-mail: rshen@illumina.com (RS); murray.sarah@scrippshealth.org (SSM)

    Affiliation: Illumina, San Diego, California, United States of America

    X
  • Sarah S Murray mail

    To whom correspondence should be addressed. E-mail: rshen@illumina.com (RS); murray.sarah@scrippshealth.org (SSM)

    Affiliation: Illumina, San Diego, California, United States of America

    ¤c Current address: Scripps Genomic Medicine, La Jolla, California, United States of America

    X
  • Published: October 05, 2007
  • DOI: 10.1371/journal.pgen.0030170

About the Authors

Michael A Eberle, Pauline C Ng, Kenneth Kuhn, Lixin Zhou, Daniel A Peiffer, Luana Galver, Karine A Viaud-Martinez, Cynthia Taylor Lawley, Kevin L Gunderson, Richard Shen, Sarah S Murray
Illumina, San Diego, California, United States of America

Corresponding Authors

Competing Interests

MAE, KK, DAP, KLG, RS, LG, KAVM, and CTL are employed by the company that makes the array chips analyzed. PCN, LZ, and SSM are former employees.

Author Contributions

MAE, PCN, KK, LZ, DAP, KLG, RS, and SSM conceived and designed the experiments. MAE, PCN, and KK performed the experiments. MAE, PCN, LG, KAVM, CTL, and SSM analyzed the data. MAE, PCN, and SSM wrote the paper.