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Research Article

Plasticity of Fission Yeast CENP-A Chromatin Driven by Relative Levels of Histone H3 and H4

  • Araceli G Castillo equal contributor,

    equal contributor Contributed equally to this work with: Araceli G Castillo, Barbara G Mellone

    Affiliation: Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom

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  • Barbara G Mellone equal contributor,

    equal contributor Contributed equally to this work with: Araceli G Castillo, Barbara G Mellone

    Affiliation: Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom

    ¤a Current address: Lawrence Berkeley National Laboratory, Berkeley, California, United States of America

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  • Janet F Partridge,

    Affiliation: Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom

    ¤b Current address: Department of Biochemistry, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America

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  • William Richardson,

    Affiliation: Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom

    ¤c Current address: Medical Research Council, Human Genetics Unit, Edinburgh, United Kingdom

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  • Georgina L Hamilton,

    Affiliation: Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom

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  • Robin C Allshire mail,

    To whom correspondence should be addressed. E-mail: Robin.Allshire@ed.ac.uk

    Affiliation: Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom

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  • Alison L Pidoux

    Affiliation: Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom

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  • Published: July 27, 2007
  • DOI: 10.1371/journal.pgen.0030121

About the Authors

Araceli G Castillo, Barbara G Mellone, Janet F Partridge, William Richardson, Georgina L Hamilton, Robin C Allshire, Alison L Pidoux
Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom

Corresponding Author

Email: Robin.Allshire@ed.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

AGC, BGM, JFP, RCA, and ALP conceived and designed the experiments. AGC, BGM, JFP, WR, GLH, and ALP performed the experiments and contributed reagents/materials/analysis tools. AGC, BGM, JFP, WR, RCA, and ALP analyzed the data. AGC, RCA, and ALP wrote the paper.