The Role of Mitochondrial DNA Mutations in Mammalian Aging

  • Gregory C Kujoth,
  • Patrick C Bradshaw,
  • Suraiya Haroon,
  • Tomas A Prolla mail

    To whom correspondence should be addressed. E-mail:

  • Published: February 23, 2007
  • DOI: 10.1371/journal.pgen.0030024

About the Authors

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Competing Interests

GCK and TAP were awarded a United States patent (7,126,040) for the PolgD257A mouse model described here. TAP is a partial owner and scientific consultant for LifeGen Technologies, specializing in the application of DNA microarray analysis to analyzing nutraceutical interventions in aging.

Author Contributions

GCK, PCB, SH, and TAP wrote the paper.