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Research Article

A High-Resolution Map of Segmental DNA Copy Number Variation in the Mouse Genome

  • Timothy A Graubert mail,

    To whom correspondence should be addressed. E-mail: graubert@medicine.wustl.edu

    Affiliation: Department of Medicine, Division of Oncology, Stem Cell Biology Section, Washington University, St. Louis, Missouri, United States of America

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  • Patrick Cahan equal contributor,

    equal contributor Contributed equally to this work with: Patrick Cahan, Deepa Edwin

    Affiliation: Department of Medicine, Division of Oncology, Stem Cell Biology Section, Washington University, St. Louis, Missouri, United States of America

    X
  • Deepa Edwin equal contributor,

    equal contributor Contributed equally to this work with: Patrick Cahan, Deepa Edwin

    Affiliation: Department of Medicine, Division of Oncology, Stem Cell Biology Section, Washington University, St. Louis, Missouri, United States of America

    X
  • Rebecca R Selzer,

    Affiliation: NimbleGen Systems, Inc., Madison, Wisconsin, United States of America

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  • Todd A Richmond,

    Affiliation: NimbleGen Systems, Inc., Madison, Wisconsin, United States of America

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  • Peggy S Eis,

    Affiliation: NimbleGen Systems, Inc., Madison, Wisconsin, United States of America

    X
  • William D Shannon,

    Affiliation: Department of Medicine, Division of General Medical Science, Washington University, St. Louis, Missouri, United States of America

    X
  • Xia Li,

    Affiliation: Department of Medicine, Division of General Medical Science, Washington University, St. Louis, Missouri, United States of America

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  • Howard L McLeod,

    Affiliation: Department of Medicine, Division of Oncology, Molecular Oncology Section, Washington University, St. Louis, Missouri, United States of America

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  • James M Cheverud,

    Affiliation: Department of Anatomy and Neurobiology, Washington University, St. Louis, Missouri, United States of America

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  • Timothy J Ley

    Affiliation: Department of Medicine, Division of Oncology, Stem Cell Biology Section, Washington University, St. Louis, Missouri, United States of America

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  • Published: January 05, 2007
  • DOI: 10.1371/journal.pgen.0030003

About the Authors

Timothy A Graubert, Patrick Cahan, Deepa Edwin, Timothy J Ley
Department of Medicine, Division of Oncology, Stem Cell Biology Section, Washington University, St. Louis, Missouri, United States of America
Rebecca R Selzer, Todd A Richmond, Peggy S Eis
NimbleGen Systems, Inc., Madison, Wisconsin, United States of America
William D Shannon, Xia Li
Department of Medicine, Division of General Medical Science, Washington University, St. Louis, Missouri, United States of America
Howard L McLeod
Department of Medicine, Division of Oncology, Molecular Oncology Section, Washington University, St. Louis, Missouri, United States of America
James M Cheverud
Department of Anatomy and Neurobiology, Washington University, St. Louis, Missouri, United States of America

Corresponding Author

Email: graubert@medicine.wustl.edu

Competing Interests

RRA, TAR, and PSE are employees of NimbleGen Systems, Inc.

Author Contributions

TAG and TJL conceived and designed the experiments. DE, RRS, TAR, and PSE performed the experiments. TAG, PC, DE, WDS, XL, HLM, and JMC analyzed the data. TAG, PC, and DE wrote the paper.