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Research Article

Selection for Unequal Densities of σ70 Promoter-Like Signals in Different Regions of Large Bacterial Genomes

  • Araceli M Huerta mail,

    To whom correspondence should be addressed. E-mail: amhuerta@ccg.unam.mx

    Affiliation: Centro de Ciencias Genómicas, Universidad Nacional Autónoma de México, Cuernavaca, México

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  • M. Pilar Francino,

    Affiliation: Evolutionary Genomics Program, Department of Energy Joint Genome Institute, and Genomics Division, Lawrence Berkeley National Laboratory, Walnut Creek, California, United States of America

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  • Enrique Morett,

    Affiliation: Departamento de Ingeniería Celular y Biocatálisis, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, México

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  • Julio Collado-Vides

    Affiliation: Centro de Ciencias Genómicas, Universidad Nacional Autónoma de México, Cuernavaca, México

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  • Published: November 10, 2006
  • DOI: 10.1371/journal.pgen.0020185

About the Authors

Araceli M Huerta, Julio Collado-Vides
Centro de Ciencias Genómicas, Universidad Nacional Autónoma de México, Cuernavaca, México
M. Pilar Francino
Evolutionary Genomics Program, Department of Energy Joint Genome Institute, and Genomics Division, Lawrence Berkeley National Laboratory, Walnut Creek, California, United States of America
Enrique Morett
Departamento de Ingeniería Celular y Biocatálisis, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, México

Corresponding Author

Email: amhuerta@ccg.unam.mx

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

AMH, MPF, and JCV conceived and designed the experiments. AMH performed the experiments. AMH, MPF, EM, and JCV analyzed the data. AMH and JCV contributed reagents/materials/analysis tools. AMH and MPF wrote the paper.