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Research Article

Functionality of Intergenic Transcription: An Evolutionary Comparison

  • Philipp Khaitovich equal contributor mail,

    equal contributor Contributed equally to this work with: Philipp Khaitovich, Janet Kelso, Henriette Franz

    To whom correspondence should be addressed. E-mail: khaitovich@eva.mpg.de

    Affiliations: Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany, Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China

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  • Janet Kelso equal contributor,

    equal contributor Contributed equally to this work with: Philipp Khaitovich, Janet Kelso, Henriette Franz

    Affiliation: Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany

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  • Henriette Franz equal contributor,

    equal contributor Contributed equally to this work with: Philipp Khaitovich, Janet Kelso, Henriette Franz

    Affiliation: Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany

    ¤ Current address: Max Planck Institute for Biophysical Chemistry, Goettingen, Germany

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  • Johann Visagie,

    Affiliation: Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany

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  • Thomas Giger,

    Affiliation: Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany

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  • Sabrina Joerchel,

    Affiliation: Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany

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  • Ekkehard Petzold,

    Affiliation: Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany

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  • Richard E Green,

    Affiliation: Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany

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  • Michael Lachmann,

    Affiliation: Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany

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  • Svante Pääbo

    Affiliation: Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany

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  • Published: October 13, 2006
  • DOI: 10.1371/journal.pgen.0020171

About the Authors

Philipp Khaitovich, Janet Kelso, Henriette Franz, Johann Visagie, Thomas Giger, Sabrina Joerchel, Ekkehard Petzold, Richard E Green, Michael Lachmann, Svante Pääbo
Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
Philipp Khaitovich
Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China

Corresponding Author

Email: khaitovich@eva.mpg.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

PK and SP conceived and designed the experiments. HF, TG, and SJ performed the experiments. PK, JK, SJ, EP, and REG analyzed the data. JK, JV, REG, ML, and SP contributed reagents/materials/analysis tools. PK, JK, REG, and SP wrote the paper.