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Research Article

Allele Frequency Matching Between SNPs Reveals an Excess of Linkage Disequilibrium in Genic Regions of the Human Genome

  • Michael A Eberle mail,

    To whom correspondence should be addressed. E-mail: eberle@u.washington.edu

    Affiliation: Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America

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  • Mark J Rieder,

    Affiliation: Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America

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  • Leonid Kruglyak,

    Affiliations: Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America, Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America

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  • Deborah A Nickerson

    Affiliation: Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America

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  • Published: September 08, 2006
  • DOI: 10.1371/journal.pgen.0020142

About the Authors

Michael A Eberle, Mark J Rieder, Deborah A Nickerson
Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America
Leonid Kruglyak
Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America
Leonid Kruglyak
Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America

Corresponding Author

Email: eberle@u.washington.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

MAE and MJR conceived and designed the experiments. MAE performed the experiments. MAE analyzed the data. MAE, MJR, LK, and DAN wrote the paper.