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Research Article

Lymphotoxin-α Gene and Risk of Myocardial Infarction in 6,928 Cases and 2,712 Controls in the ISIS Case-Control Study

  • Robert Clarke equal contributor mail,

    equal contributor Contributed equally to this work with: Robert Clarke, Peng Xu

    To whom correspondence should be addressed. E-mail: robert.clarke@ctsu.ox.ac.uk

    Affiliation: Clinical Trial Service Unit, Old Road Campus, Oxford, United Kingdom

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  • Peng Xu equal contributor,

    equal contributor Contributed equally to this work with: Robert Clarke, Peng Xu

    Affiliation: Centre National de Genotypage, Paris, France

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  • Derrick Bennett,

    Affiliation: Clinical Trial Service Unit, Old Road Campus, Oxford, United Kingdom

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  • Sarah Lewington,

    Affiliation: Clinical Trial Service Unit, Old Road Campus, Oxford, United Kingdom

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  • Krina Zondervan,

    Affiliation: Wellcome Trust Centre for Human Genetics, Old Road Campus, Oxford, United Kingdom

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  • Sarah Parish,

    Affiliation: Clinical Trial Service Unit, Old Road Campus, Oxford, United Kingdom

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  • Alison Palmer,

    Affiliation: Clinical Trial Service Unit, Old Road Campus, Oxford, United Kingdom

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  • Sarah Clark,

    Affiliation: Clinical Trial Service Unit, Old Road Campus, Oxford, United Kingdom

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  • Lon Cardon,

    Affiliation: Wellcome Trust Centre for Human Genetics, Old Road Campus, Oxford, United Kingdom

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  • Richard Peto,

    Affiliation: Clinical Trial Service Unit, Old Road Campus, Oxford, United Kingdom

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  • Mark Lathrop,

    Affiliation: Centre National de Genotypage, Paris, France

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  • Rory Collins, for the International Study of Infarct Survival (ISIS) Collaborators

    Affiliation: Clinical Trial Service Unit, Old Road Campus, Oxford, United Kingdom

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  • Published: July 07, 2006
  • DOI: 10.1371/journal.pgen.0020107

About the Authors

Robert Clarke, Derrick Bennett, Sarah Lewington, Sarah Parish, Alison Palmer, Sarah Clark, Richard Peto, Rory Collins
Clinical Trial Service Unit, Old Road Campus, Oxford, United Kingdom
Peng Xu, Mark Lathrop
Centre National de Genotypage, Paris, France
Krina Zondervan, Lon Cardon
Wellcome Trust Centre for Human Genetics, Old Road Campus, Oxford, United Kingdom

Corresponding Author

Email: robert.clarke@ctsu.ox.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

R. Clarke, P. Xu, D. Bennett, S. Parish, R. Peto, M. Lathrop, and R. Collins conceived and designed the experiments. R. Clarke, P. Xu, D. Bennett, S. Clark, M. Lathrop, and R. Collins performed the experiments. R. Clarke, P. Xu, D. Bennett, S. Lewington, K. Zondervan, S. Parish, A. Palmer, L. Cardon, M. Lathrop, and R. Collins analyzed the data. R. Clarke, P. Xu, R. Peto, M. Lathrop, and R. Collins contributed reagents/materials/analysis tools. R. Clarke, P. Xu, D. Bennett, S. Lewington, K. Zondervan, S. Parish, A. Palmer, L. Cardon, R. Peto, M. Lathrop, and R. Collins wrote the paper.