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Research Article

Sox6 Directly Silences Epsilon Globin Expression in Definitive Erythropoiesis

  • Zanhua Yi equal contributor,

    equal contributor Contributed equally to this work with: Zanhua Yi, Orit Cohen-Barak

    Affiliation: Department of Pediatrics, University of Arizona, College of Medicine, Tucson, Arizona, United States of America

    X
  • Orit Cohen-Barak equal contributor,

    equal contributor Contributed equally to this work with: Zanhua Yi, Orit Cohen-Barak

    Affiliation: Department of Pediatrics, University of Arizona, College of Medicine, Tucson, Arizona, United States of America

    X
  • Nobuko Hagiwara,

    Affiliation: Department of Internal Medicine, Division of Cardiovascular Medicine, University of California Davis, Davis, California, United States of America

    X
  • Paul D Kingsley,

    Affiliation: Department of Pediatrics, Center for Pediatric Biomedical Research, University of Rochester Medical Center, Rochester, New York, United States of America

    X
  • Deborah A Fuchs,

    Affiliation: Department of Pathology, University of Arizona, College of Medicine, Tucson, Arizona, United States of America

    X
  • Drew T Erickson,

    Affiliation: Department of Pediatrics, University of Arizona, College of Medicine, Tucson, Arizona, United States of America

    X
  • Elliot M Epner,

    Affiliation: Department of Hematology & Oncology, Oregon Health & Science University, Portland, Oregon, United States of America

    X
  • James Palis,

    Affiliation: Department of Pediatrics, Center for Pediatric Biomedical Research, University of Rochester Medical Center, Rochester, New York, United States of America

    X
  • Murray H Brilliant mail

    To whom correspondence should be addressed. E-mail: mhb@peds.arizona.edu

    Affiliation: Department of Pediatrics, University of Arizona, College of Medicine, Tucson, Arizona, United States of America

    X
  • Published: February 03, 2006
  • DOI: 10.1371/journal.pgen.0020014

About the Authors

Zanhua Yi, Orit Cohen-Barak, Drew T Erickson, Murray H Brilliant
Department of Pediatrics, University of Arizona, College of Medicine, Tucson, Arizona, United States of America
Nobuko Hagiwara
Department of Internal Medicine, Division of Cardiovascular Medicine, University of California Davis, Davis, California, United States of America
Paul D Kingsley, James Palis
Department of Pediatrics, Center for Pediatric Biomedical Research, University of Rochester Medical Center, Rochester, New York, United States of America
Deborah A Fuchs
Department of Pathology, University of Arizona, College of Medicine, Tucson, Arizona, United States of America
Elliot M Epner
Department of Hematology & Oncology, Oregon Health & Science University, Portland, Oregon, United States of America

Corresponding Author

Email: mhb@peds.arizona.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

ZY and OCB conceived, designed, and performed the experiments. ZY, OCB, and MHB analyzed the data. NH, PDK, DAF, DTE, EME, JP, and MHB contributed reagents/materials/analysis tools. JP contributed to the discussion. ZY and OCB wrote the paper.