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Research Article

Gain and Loss of Multiple Genes During the Evolution of Helicobacter pylori

  • Helga Gressmann,

    Affiliation: Department of Molecular Biology, Max-Planck-Institut für Infektionsbiologie, Berlin, Germany

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  • Bodo Linz,

    Affiliation: Department of Molecular Biology, Max-Planck-Institut für Infektionsbiologie, Berlin, Germany

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  • Rohit Ghai,

    Affiliation: Institut für Medizinische Mikrobiologie, Justus-Liebig-Universität, Giessen, Germany

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  • Klaus-Peter Pleissner,

    Affiliation: Core Facility Bioinformatics, Max-Planck-Institut für Infektionsbiologie, Berlin, Germany

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  • Ralph Schlapbach,

    Affiliation: Functional Genomics Center Zurich, ETH Zurich/University of Zurich, Zurich, Switzerland

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  • Yoshio Yamaoka,

    Affiliation: Department of Medicine, M.E. DeBakey Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas, United States of America

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  • Christian Kraft,

    Affiliation: Medizinische Hochschule Hannover, Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Hannover, Germany

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  • Sebastian Suerbaum,

    Affiliation: Medizinische Hochschule Hannover, Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Hannover, Germany

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  • Thomas F Meyer,

    Affiliation: Department of Molecular Biology, Max-Planck-Institut für Infektionsbiologie, Berlin, Germany

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  • Mark Achtman mail

    To whom correspondence should be addressed. E-mail: achtman@mpiib-berlin.mpg.de

    Affiliation: Department of Molecular Biology, Max-Planck-Institut für Infektionsbiologie, Berlin, Germany

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  • Published: October 07, 2005
  • DOI: 10.1371/journal.pgen.0010043

About the Authors

Helga Gressmann, Bodo Linz, Thomas F Meyer, Mark Achtman
Department of Molecular Biology, Max-Planck-Institut für Infektionsbiologie, Berlin, Germany
Rohit Ghai
Institut für Medizinische Mikrobiologie, Justus-Liebig-Universität, Giessen, Germany
Klaus-Peter Pleissner
Core Facility Bioinformatics, Max-Planck-Institut für Infektionsbiologie, Berlin, Germany
Ralph Schlapbach
Functional Genomics Center Zurich, ETH Zurich/University of Zurich, Zurich, Switzerland
Yoshio Yamaoka
Department of Medicine, M.E. DeBakey Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas, United States of America
Christian Kraft, Sebastian Suerbaum
Medizinische Hochschule Hannover, Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Hannover, Germany

Corresponding Author

Email: achtman@mpiib-berlin.mpg.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

SS, TFM, and MA conceived and designed the experiments. HG performed the experiments. HG, BL, KPP, and RS analyzed the data. RG, YY, and CK contributed reagents/materials/analysis tools. MA wrote the paper.