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Research Article

Genetic Interactions Due to Constitutive and Inducible Gene Regulation Mediated by the Unfolded Protein Response in C. elegans

  • Xiaohua Shen,

    Affiliation: Howard Hughes Medical Institute, Department of Biological Chemistry, University of Michigan Medical Center, Ann Arbor, Michigan, United States of America

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  • Ronald E Ellis,

    Affiliation: Department of Molecular Biology, The UMDNJ School of Osteopathic Medicine, Stratford, New Jersey, United States of America

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  • Kenjiro Sakaki,

    Affiliation: Howard Hughes Medical Institute, Department of Biological Chemistry, University of Michigan Medical Center, Ann Arbor, Michigan, United States of America

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  • Randal J Kaufman mail

    To whom correspondence should be addressed. E-mail: kaufmanr@umich.edu

    Affiliation: Howard Hughes Medical Institute, Department of Biological Chemistry, University of Michigan Medical Center, Ann Arbor, Michigan, United States of America

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  • Published: September 23, 2005
  • DOI: 10.1371/journal.pgen.0010037

About the Authors

Xiaohua Shen, Kenjiro Sakaki, Randal J Kaufman
Howard Hughes Medical Institute, Department of Biological Chemistry, University of Michigan Medical Center, Ann Arbor, Michigan, United States of America
Ronald E Ellis
Department of Molecular Biology, The UMDNJ School of Osteopathic Medicine, Stratford, New Jersey, United States of America

Corresponding Author

Email: kaufmanr@umich.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

XS, REE, and RJK conceived and designed the experiments. XS performed the experiments. KS provided technical assistance on quantitative RT-PCR. XS and RJK analyzed the data. XS, REE, and RJK wrote the paper.