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Research Article

Assumption-Free Estimation of Heritability from Genome-Wide Identity-by-Descent Sharing between Full Siblings

  • Peter M Visscher mail,

    To whom correspondence should be addressed. E-mail: peter.visscher@qimr.edu.au

    Affiliation: Genetic Epidemiology Group, Queensland Institute of Medical Research, Brisbane, Australia

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  • Sarah E Medland,

    Affiliation: Genetic Epidemiology Group, Queensland Institute of Medical Research, Brisbane, Australia

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  • Manuel A. R Ferreira,

    Affiliation: Genetic Epidemiology Group, Queensland Institute of Medical Research, Brisbane, Australia

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  • Katherine I Morley,

    Affiliation: Genetic Epidemiology Group, Queensland Institute of Medical Research, Brisbane, Australia

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  • Gu Zhu,

    Affiliation: Genetic Epidemiology Group, Queensland Institute of Medical Research, Brisbane, Australia

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  • Belinda K Cornes,

    Affiliation: Genetic Epidemiology Group, Queensland Institute of Medical Research, Brisbane, Australia

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  • Grant W Montgomery,

    Affiliation: Genetic Epidemiology Group, Queensland Institute of Medical Research, Brisbane, Australia

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  • Nicholas G Martin

    Affiliation: Genetic Epidemiology Group, Queensland Institute of Medical Research, Brisbane, Australia

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  • Published: March 24, 2006
  • DOI: 10.1371/journal.pgen.0020041

Reader Comments (1)

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Assumption-free, or fewer assumptions?

Posted by miko on 06 Oct 2009 at 20:35 GMT

This is not my field, but it seems the authors have removed assumptions about genetic variance, but no others. Don't the heritabilty estimates still include assumptions like no epistatic interactions and no gene x environment interactions?

No competing interests declared.