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Research Article

Raf1 Is a DCAF for the Rik1 DDB1-Like Protein and Has Separable Roles in siRNA Generation and Chromatin Modification

  • Alessia Buscaino,

    Affiliation: Wellcome Trust Centre for Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh, United Kingdom

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  • Sharon A. White,

    Affiliation: Wellcome Trust Centre for Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh, United Kingdom

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  • Douglas R. Houston,

    Affiliation: Wellcome Trust Centre for Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh, United Kingdom

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  • Erwan Lejeune,

    Affiliation: Wellcome Trust Centre for Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh, United Kingdom

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  • Femke Simmer,

    Affiliation: Wellcome Trust Centre for Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh, United Kingdom

    Current address: Department of Molecular Biology, NCMLS, Radboud University Nijmegen, Nijmegen, The Netherlands

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  • Flavia de Lima Alves,

    Affiliation: Wellcome Trust Centre for Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh, United Kingdom

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  • Piyush T. Diyora,

    Affiliation: Wellcome Trust Centre for Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh, United Kingdom

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  • Takeshi Urano,

    Affiliation: Department of Biochemistry, Shimane University Faculty of Medicine, Izumo, Japan

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  • Elizabeth H. Bayne,

    Affiliation: Wellcome Trust Centre for Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh, United Kingdom

    Current address: Wellcome Trust Centre for Gene Regulation and Expression, College of Life Sciences, University of Dundee, Dundee, United Kingdom

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  • Juri Rappsilber,

    Affiliation: Wellcome Trust Centre for Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh, United Kingdom

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  • Robin C. Allshire mail

    robin.allshire@ed.ac.uk

    Affiliation: Wellcome Trust Centre for Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh, United Kingdom

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  • Published: February 02, 2012
  • DOI: 10.1371/journal.pgen.1002499

Reader Comments (2)

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Publisher's Note: Correction to Figure 5

Posted by PLoS_Genetics on 10 Apr 2012 at 09:28 GMT

Raf1 mutations disrupt interaction with Rik1.
http://plosgenetics.org/article/info:doi/10.1371/journal.pgen.1002499#pgen-1002499-g005

The labelling on the columns in Figure 5C is in the wrong order and should read from left to right: no FLAG; FLAG-Raf1; FLAG-Raf1R518A; FLAG-Raf1R576A. You can view the correct Figure 5 here: http://www.plosgenetics.org/corrections/pgen.1002499.g005.cn.tif

No competing interests declared.