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Research Article

Mixed Effects Modeling of Proliferation Rates in Cell-Based Models: Consequence for Pharmacogenomics and Cancer

  • Hae Kyung Im mail,

    haky@uchicago.edu

    Affiliation: Department of Health Studies, University of Chicago, Chicago, Illinois, United States of America

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  • Eric R. Gamazon,

    Affiliation: Department of Medicine, University of Chicago, Chicago, Illinois, United States of America

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  • Amy L. Stark,

    Affiliation: Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America

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  • R. Stephanie Huang,

    Affiliation: Department of Medicine, University of Chicago, Chicago, Illinois, United States of America

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  • Nancy J. Cox,

    Affiliations: Department of Medicine, University of Chicago, Chicago, Illinois, United States of America, Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America

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  • M. Eileen Dolan

    Affiliation: Department of Medicine, University of Chicago, Chicago, Illinois, United States of America

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  • Published: February 09, 2012
  • DOI: 10.1371/journal.pgen.1002525

Reader Comments (4)

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Prop Starmans

Posted by haky on 02 Aug 2012 at 21:41 GMT

Nevertheless, 80% of the Starmans' proliferation genes had a positive effect on LCL growth rate.
http://plosgenetics.org/article/info:doi/10.1371/journal.pgen.1002525#article1.body1.sec2.sec6.p1

The proportion of Starman's proliferation genes with positive effect was 47%.

No competing interests declared.