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Research Article

Deep Sequencing of Plant and Animal DNA Contained within Traditional Chinese Medicines Reveals Legality Issues and Health Safety Concerns

  • Megan L. Coghlan,

    Affiliation: Australian Wildlife Forensic Services and Ancient DNA Laboratory, School of Biological Sciences and Biotechnology, Murdoch University, Murdoch, Australia

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  • James Haile,

    Affiliation: Australian Wildlife Forensic Services and Ancient DNA Laboratory, School of Biological Sciences and Biotechnology, Murdoch University, Murdoch, Australia

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  • Jayne Houston,

    Affiliation: Australian Wildlife Forensic Services and Ancient DNA Laboratory, School of Biological Sciences and Biotechnology, Murdoch University, Murdoch, Australia

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  • Dáithí C. Murray,

    Affiliation: Australian Wildlife Forensic Services and Ancient DNA Laboratory, School of Biological Sciences and Biotechnology, Murdoch University, Murdoch, Australia

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  • Nicole E. White,

    Affiliation: Australian Wildlife Forensic Services and Ancient DNA Laboratory, School of Biological Sciences and Biotechnology, Murdoch University, Murdoch, Australia

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  • Paula Moolhuijzen,

    Affiliation: Centre for Comparative Genomics, Murdoch University, Murdoch, Australia

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  • Matthew I. Bellgard,

    Affiliation: Centre for Comparative Genomics, Murdoch University, Murdoch, Australia

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  • Michael Bunce mail

    m.bunce@murdoch.edu.au

    Affiliation: Australian Wildlife Forensic Services and Ancient DNA Laboratory, School of Biological Sciences and Biotechnology, Murdoch University, Murdoch, Australia

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  • Published: April 12, 2012
  • DOI: 10.1371/journal.pgen.1002657

Reader Comments (1)

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Revolutionize CTM

Posted by zkzlzx on 07 May 2012 at 08:12 GMT

As for the toxic plants in the CTM, I think there are three sources: a, the toxic plants are mixed in the raw material by accident during collection in the field because of similar appearences. b, the elements of toxic plants, as contents of other medicine, find the way to the target medicine by, for examplem, powder in the air, we can call it "contamination", and even minor amouts can be detected by next-generation sequencing technology. c, the toxic plants may be just useful components of the medicine, but they are kept for secrete for commercial purpose.

No competing interests declared.