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Research Article

No Influence of Indy on Lifespan in Drosophila after Correction for Genetic and Cytoplasmic Background Effects

  • Janne M Toivonen,

    Affiliations: Department of Biology, University College London, London, United Kingdom, Institute of Medical Technology and Tampere University Hospital, FI-33014, University of Tampere, Tampere, Finland

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  • Glenda A Walker,

    Affiliation: Department of Biology, University College London, London, United Kingdom

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  • Pedro Martinez-Diaz,

    Affiliation: Department of Biology, University College London, London, United Kingdom

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  • Ivana Bjedov,

    Affiliation: Department of Biology, University College London, London, United Kingdom

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  • Yasmine Driege,

    Affiliation: Department of Biology, University College London, London, United Kingdom

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  • Howard T Jacobs,

    Affiliation: Institute of Medical Technology and Tampere University Hospital, FI-33014, University of Tampere, Tampere, Finland

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  • David Gems,

    Affiliation: Department of Biology, University College London, London, United Kingdom

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  • Linda Partridge mail

    To whom correspondence should be addressed. E-mail: l.partridge@ucl.ac.uk

    Affiliation: Department of Biology, University College London, London, United Kingdom

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  • Published: June 15, 2007
  • DOI: 10.1371/journal.pgen.0030095

Reader Comments (1)

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How Many More "Mutations" are Wolbachia-Host Artefacts?

Posted by PLoS_Genetics on 20 Feb 2008 at 11:32 GMT

Originally submitted as a Reader Response by Jason Rasgon (jrasgon@jhsph.edu) on 19 June 2007:

This is a very important paper detailing the oft-overlooked effect of Wolbachia on the physiology of its host. This phenomenon has been recognized in the Wolbachia community for years, but when I mention this possibility to my Drosophila-researcher colleagues, I often get a shrug. It is high time that those in the Drosophila field begin to pay attention to the potential confounding effect of Wolbachia infection on their experimental results. How many more "mutations" will have to be re-evaluated?