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Research Article

Nuclear Pore Proteins Nup153 and Megator Define Transcriptionally Active Regions in the Drosophila Genome

  • Juan M. Vaquerizas equal contributor,

    equal contributor Contributed equally to this work with: Juan M. Vaquerizas, Ritsuko Suyama, Jop Kind

    Affiliation: European Bioinformatics Institute, Cambridge, United Kingdom

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  • Ritsuko Suyama equal contributor,

    equal contributor Contributed equally to this work with: Juan M. Vaquerizas, Ritsuko Suyama, Jop Kind

    Affiliation: Genome Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany

    X
  • Jop Kind equal contributor,

    equal contributor Contributed equally to this work with: Juan M. Vaquerizas, Ritsuko Suyama, Jop Kind

    Affiliation: Genome Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany

    X
  • Kota Miura,

    Affiliation: Centre for Molecular and Cellular Imaging, European Molecular Biology Laboratory, Heidelberg, Germany

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  • Nicholas M. Luscombe mail,

    akhtar@immunbio.mpg.de (AA); luscombe@ebi.ac.uk (NML)

    Affiliations: European Bioinformatics Institute, Cambridge, United Kingdom, Genome Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany

    These authors are joint senior authors on this work.

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  • Asifa Akhtar mail

    akhtar@immunbio.mpg.de (AA); luscombe@ebi.ac.uk (NML)

    Affiliations: Genome Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany, Laboratory of Chromatin Regulation, Max Planck Institute of Immunobiology, Freiburg, Germany

    These authors are joint senior authors on this work.

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  • Published: February 12, 2010
  • DOI: 10.1371/journal.pgen.1000846
  • Featured in PLOS Collections

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Accompanying Perspective: http://www.plosgenetics.org/doi/pgen.1000861

Posted by PLoS_Genetics on 26 Feb 2010 at 09:24 GMT

Here we establish nucleoporins as a major class of global regulators for gene expression in Drosophila melanogaster.
http://plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000846#article1.front1.article-meta1.abstract1.p1

An accompanying Perspective by Kohta Ikegami and Jason D. Lieb is available here: http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000861

No competing interests declared.