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Research Article

A Novel Role for Mc1r in the Parallel Evolution of Depigmentation in Independent Populations of the Cavefish Astyanax mexicanus

  • Joshua B. Gross,

    Affiliation: Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Richard Borowsky,

    Affiliation: Cave Biology Research Group, Department of Biology, New York University, New York, New York, United States of America

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  • Clifford J. Tabin mail

    tabin@genetics.med.harvard.edu

    Affiliation: Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Published: January 02, 2009
  • DOI: 10.1371/journal.pgen.1000326

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Related Perspective

Posted by PLoS_Genetics on 20 Mar 2009 at 10:29 GMT

This example of parallelism indicates that certain genes are frequent targets of mutation in the repeated evolution of regressive phenotypes in cave-adapted species.
http://plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000326#article1.front1.article-meta1.abstract1.p1

- http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000388 (Conservation and Convergence of Colour Genetics: MC1R Mutations in brown Cavefish by Nicholas I. Mundy)

No competing interests declared.