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Research Article

Contrasting Mode of Evolution at a Coat Color Locus in Wild and Domestic Pigs

  • Meiying Fang equal contributor,

    equal contributor Contributed equally to this work with: Meiying Fang, Greger Larson

    Affiliations: Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden, College of Animal Science and Technology, China Agricultural University, Beijing, China

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  • Greger Larson equal contributor,

    equal contributor Contributed equally to this work with: Meiying Fang, Greger Larson

    Affiliation: Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden

    Current address: Department of Archaeology, Durham University, Durham, United Kingdom

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  • Helena Soares Ribeiro,

    Affiliation: Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden

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  • Ning Li,

    Affiliation: State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China

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  • Leif Andersson mail

    Leif.Andersson@imbim.uu.se

    Affiliations: Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden

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  • Published: January 16, 2009
  • DOI: 10.1371/journal.pgen.1000341

Reader Comments (4)

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Comment on dN/dS

Posted by lwycau on 18 Jan 2010 at 01:26 GMT

I am skeptical of the dS/dN analysis, and believe the higher %dS values is an artifact of the method you used to estimate substitution rates (often exceeding 1), which means that the actual estimate will be sensitive to the mutation model.

No competing interests declared.