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Research Article

Inferring the Joint Demographic History of Multiple Populations from Multidimensional SNP Frequency Data

  • Ryan N. Gutenkunst mail,

    ryang@lanl.gov

    Affiliation: Theoretical Biology and Biophysics and Center for Nonlinear Studies, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

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  • Ryan D. Hernandez,

    Affiliation: Human Genetics, University of Chicago, Chicago, Illinois, United States of America

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  • Scott H. Williamson,

    Affiliation: Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America

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  • Carlos D. Bustamante

    Affiliation: Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America

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  • Published: October 23, 2009
  • DOI: 10.1371/journal.pgen.1000695

Reader Comments (1)

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Recent data supports resettlement of Europe

Posted by RyanGutenkunst on 25 Oct 2009 at 18:31 GMT

Other studies [11],[12] have estimated divergence times between Europeans and East Asians similar to the ≈23 kya we infer. Interestingly, archeological evidence places humans in Europe much earlier (≈40 kya) [1].
http://plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000695#article1.body1.sec4.p3

A recent article in Science ( http://dx.doi.org/10.1126/science.1176869 ) compared mtDNA from ancient European hunter-gathers, more recent European farmers, and contemporary Europeans. They found that the ancient hunter-gatherers contributed little to the contemporary gene pool, suggesting that contemporary Europeans are descended primarily from more recent migrants into Europe. This is consistent with our relatively recent inferred date for European-Asian divergence.

No competing interests declared.