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Research Article

The Genographic Project Public Participation Mitochondrial DNA Database

  • Doron M Behar,

    Affiliations: Genomics Research Center, Family Tree DNA, Houston, Texas, United States of America, Molecular Medicine Laboratory, Rambam Health Care Campus, Haifa, Israel

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  • Saharon Rosset,

    Affiliation: Data Analytics Research Group, IBM T. J. Watson Research Center, Yorktown Heights, New York, United States of America

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  • Jason Blue-Smith,

    Affiliation: The Genographic Project, National Geographic Society, Washington, District of Columbia, United States of America

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  • Oleg Balanovsky,

    Affiliation: Research Centre for Medical Genetics, Russian Academy of Medical Sciences, Moscow, Russia

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  • Shay Tzur,

    Affiliation: Genomics Research Center, Family Tree DNA, Houston, Texas, United States of America

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  • David Comas,

    Affiliation: Unitat de Biologia Evolutiva, Universitat Pompeu Fabra, Barcelona, Spain

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  • R. John Mitchell,

    Affiliation: Department of Genetics, La Trobe University, Bundoora, Australia

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  • Lluis Quintana-Murci,

    Affiliations: Institut Pasteur, Paris, France, CNRS, URA3012, Paris, France

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  • Chris Tyler-Smith,

    Affiliation: The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

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  • R. Spencer Wells mail,

    To whom correspondence should be addressed. E-mail: genopubs@ngs.org

    Affiliation: The Genographic Project, National Geographic Society, Washington, District of Columbia, United States of America

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  • The Genographic Consortium
  • Published: June 29, 2007
  • DOI: 10.1371/journal.pgen.0030104

Reader Comments (2)

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Neanderthal mtDNA

Posted by GeneHays on 29 Jul 2008 at 22:38 GMT

Your article says, "...distinguishes these Neanderthal sequences from modern humans. While all of these five mutations have in fact been observed in our full database of 78,590 samples, no combination of any two (2) of them has appeared in any sample." But, as I compared my mtDNA results to the mtDNA extracted from ancient Neanderthal bones, I found three (3) of my differences (A263G, T16189C, and A16299G) within the Neanderthal results.
See www.isogg.org/neanderthal...

My mtDNA
Haplogroups = H*
(GENBANK) ACCESSION # EU677425 ~ Complete Genome
A263G 309.C 309.C 315.C A750G A1438G A4769G A8860G A15326G T16189C A16299G T16422C T16519C
HVR1 differences = 16189C, 16299G, 16422C, 16519C
HVR2 differences = 263G, 309.1C, 309.2C, 315.1C
CR differences, Full Genome = 750G, 1438G, 4769G, 8860G, 15326G