"Jenny has had a long and joyful career, overcoming a near fatal illness and a coincident collapse in funding to resurrect her research, and eventually being awarded the L'Oreal Prize for women in science." Read more in Jane Gitschier's Interview with Jenny Graves.
These observations suggest that the local arrangement of binding sites relative to each other is more important than their overall arrangement into larger units of cis-regulatory function.
The authors provide evidence that sample size has a greater impact on the power of whole-genome association studies than SNP density or genetic coverage.
This work shows that epigenetic reprogramming is crucial for maintaining the pluripotency of germ and embryonic stem cells.
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PLoS Biology; PLoS Medicine; PLoS Computational Biology; PLoS Neglected Tropical Diseases
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